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KMID : 0388220110180040315
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Journal of the Korean Rheumatism Association
2011 Volume.18 No. 4 p.315 ~ p.319
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A Case of Ankylosing Spondylitis with Follicular Lymphoma
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Park Hee-Jin
Park Yoon-Hye
Park Kyeong-Hye
Kim Mi-Hyun
Choe Eun-Yeong
Han Jeong-Woo
Hong Ji-Young
Chang Myung-Hee
Kim Sun-Jung
Shim Joo-Eun
Kie Jeong-Hae
Lee Sang-Won
Park Yong-Beom
Lee Soo-Kon
Lee Chan-Hee
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Abstract
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Several autoimmune and chronic inflammatory conditions have been consistently linked with an increased risk of hematologic malignancies. Although ankylosing spondylitis (AS) is a chronic inflammatory disease, previous studies have demonstrated that it is not associated with an increase in risk of malignant lymphomas. Cases of AS accompanied by hematologic malignancies such as multiple myeloma, chronic myelogenous leukemia, and Hodgkin’s disease have been reported. In Korea, AS with non- Hodgkin’s lymphoma or follicular lymphoma has not been reported. We experienced a 38-year-old male who had been diagnosed with follicular lymphoma with bone metastasis, who achieved complete remission after having been treated with chemotherapy, developed new inflammatory back pain. An MRI of his hip showed an active inflammation of the left sacroiliac joint and a positive HLA-B27. The patient was diagnosed with AS and was treated with naproxen, which improved the pain in his back and buttock.
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KEYWORD
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Ankylosing spondylitis, Non-Hodgkin’s lymphoma, Follicular lymphoma, Inflammatory back pain
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